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ABCB11 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
ATP Binding Cassette Subfamily B Member 11
Descriptor
Spanish
:
Miembro 11 de la Subfamilia B de Transportador de Casetes de Unión al ATP
Descriptor
Portuguese
:
Membro 11 da Subfamília B de Transportadores de Cassetes de Ligação de ATP
Synonyms
English
:
ABCB11 Protein
BSEP Protein
Bile Salt Export Pump
Tree Number:
D12.776.157.530.100.652.438
D12.776.157.530.450.074.500.500.875.438
D12.776.395.550.020.610.534
D12.776.543.550.192.610.534
D12.776.543.585.100.610.438
D12.776.543.585.450.074.500.500.875.438
Definition
English
:
An ATP-binding cassette, sub-family B protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the
BILE CANALICULI
of
HEPATOCYTES
.
Mutations
in the ABCB11 gene are associated with progressive familial intrahepatic
cholestasis
2 (see
CHOLESTASIS
, INTRAHEPATIC).
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57076
Unique Identifier:
D000074020
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS